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KMID : 0648320130190010017
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Journal of The Korean Society of Hypertension
2013 Volume.19 No. 1 p.17 ~ p.22
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Renal Sodium Transporters and Water Channels
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Kim Hye-Young
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Abstract
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Hypertension is closely related to salt and water retention. The kidney plays an important role in the blood pressure regulation primarily to modulating tubular sodium and water reabsorption. The regulation of the salt and water balance depends upon an array of solute and water channels in the renal tubules. An altered regulation of sodium and water channels in the kidney may be related to various pathological conditions associated with altered salt and water retention. This review will discuss renal handling of sodium and water, with particular emphasis on aquaporins and renal sodium transporters and channels.
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KEYWORD
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Aquaporins, Sodium, Membrane transport proteins, Kidney
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